PANATHINAIKOS v RANGERS
Panathinaikos are facing injury problems with Romania midfielder Lucian Sanmartean missing training since picking up a knee injury in Saturday's 2-0 win over Ionikos, which kept them top of the Greek league.
Greece goalkeeper Antonis Nikopolidis will also miss the game after getting injured in the first half of their 5-0 defeat at Manchester United a fortnight ago.
Rangers will be without Scotland striker Steven Thompson, who was told on Monday he is likely to require a knee operation and could be missing for the next six months.
Maurice Ross sustained a hamstring injury in Saturday's 3-1 league win over Dundee and Georgian central defender Zurab Zhizanishvili could replace him at right full back.
Rangers captain Craig Moore has recovered from a hamstring problem and is likely to partner Henning Berg in central defence, but Dutch players Ronald de Boer and Fernando Ricksen remain on the injured list.
Panathinaikos: 12-Costas Halkias; 3-Nasif Morris, 16-Sotiris Kyrgiakos, 30-Takis Fyssas, 14-Raymond Zaoutoustas; 27-Pantelis Konstantinidis, 20-Angelos Basinas, 35-Jan Michaelsen, 4-Silvio Maric; 11-Dimitris Papadopoulos, 19-Michalis Konstantinou
Rangers: 1-Stefan Klos; 15-Zurab Khizanishvili, 25-Henning Berg, 3-Craig Moore, 18-Michael Ball; 4-Emerson, 23-Mikel Arteta, 8-Christian Nerlinger; 26-Peter Lovenkrands, 10-Michael Mols, 7-Shota Arveladze.
Referee: Arturo Dauden Ibanez (Spain)
VfB STUTTGART v MANCHESTER UNITED
Stuttgart have no major injury worries and are on a high after extending their brilliant Bundesliga start with a convincing 3-0 win at TSV 1860 Munich on Saturday. Coach Felix Magath's men top the standings and are the only side yet to lose a match or concede a goal seven games into the season.
"We're having a good run at the moment and we believe we can get a result against Manchester United," said Croatian midfielder and captain Zvonimir Soldo. Another man United need to watch is gifted Belarus midfielder Alexander Gleb, who scored a superb goal on Saturday.
Stuttgart, last season's Bundesliga runners-up, started their Champions League campaign with a 2-1 defeat by Rangers but Magath said: "We're not happy with doing well just in the Bundesliga -- we also want to make an impact in Europe."
France defender Mikael Silvestre is set to return for United after recovering from a knee injury that kept him out of United's 4-1 win at Leicester City on Saturday. He is likely to resume his central defensive partnership with Rio Ferdinand, with John O'Shea reverting to the left-back role.
With England midfielder Paul Scholes making a successful comeback at Leicester, United are missing only long-term injury victims Ole Gunnar Solskjaer (knee), Wes Brown (knee) and Kleberson (shoulder).
Stuttgart: 1-Timo Hildebrand; 2-Andreas Hinkel, 6-Fernando Meira, 5-Marcelo Bordon, 21-Philipp Lahm; 20-Zvonimir Soldo, 8-Jurica Vranjes, 19-Horst Heldt, 19-Alexander Gleb; 22-Kevin Kuranyi, 18-Cacau.
United: 14-Tim Howard; 2-Gary Neville, 5-Rio Ferdinand, 27-Mikael Silvestre, 22-John O'Shea; 11-Ryan Giggs, 16-Roy Keane, 3-Phil Neville, 25-Quinton Fortune; 18-Paul Scholes; 10-Ruud Van Nistelrooy.
Referee: Cosimo Bolognino (Italy)
PORTO v REAL MADRID
Porto have had closed training sessions since Sunday but few surprises are expected when they line up against Real Madrid with just Russian midfielder Dmitri Alenitchev (thigh) on the injury list.
The Portuguese champions have been slow to find the form which won them a domestic league and cup double, plus the UEFA Cup, last season and playmaker Deco Souza has been notably below par.
However, Jose Mourinho's side have finally pulled clear at the top of the Portuguese league after beating Vitoria Guimaraes 2-1 away at the weekend.
Real will be missing the in-form David Beckham from their midfield, the England captain having sustained an injury to the sole of his right foot during Saturday's 2-0 league defeat against Valencia.
Versatile defender Ivan Helguera is set to return after recovering from a throat infection that kept him out of the Valencia game and may be asked to move up to his former position in the centre of midfield to cover for Beckham.
Club captain and joint top-scorer Raul was left out of the provisional squad due to a hip injury, but was then included after passing a late fitness test on Tuesday.
Young striker Javier Portillo would take his place up front alongside Ronaldo if the Spanish international suffered any further setback, while Guti may replace Esteban Cambiasso in midfield after the Argentine's poor performance at the Mestalla.
Porto: 99-Vitor Baia; 22-Paulo Ferreira, 2-Jorge Costa, 4-Ricardo Carvalho, 8-Nuno Valente; 18-Maniche Ribeiro, 6-Francisco Costinha, 10-Deco Souza, 25-Ricardo Fernandes; 77-Benni McCarthy, 11-Derlei Silva
Real Madrid: 1-Iker Casillas; 2-Michel Salgado, 22-Francisco Pavon, 15-Raul Bravo, 3-Roberto Carlos; 10-Luis Figo, 14-Guti, 6-Ivan Helguera, 5-Zinedine Zidane; 7-Raul, 9-Ronaldo
Referee: Pierluigi Collina (Italy)
OLYMPIQUE MARSEILLE v PARTIZAN BELGRADE
Marseille could be without Senegal defender Habib Beye and mdifielder Brahim Hemdani, arguably the best two players in their team's 4-2 defeat by Real Madrid in their group F opener.
Beye has a broken rib while Hemdani has a thigh injury and both are doubtful.
Partizan face a goalkeeping crisis as Ivica Kralj is still sidelined with a knee injury while reserve keeper Djordje Pantic twisted his ankle in training on Sunday, leaving Radovan Radakovic as the first-choice option and 19-year-old Nemanja Jovsic as the only alternative.
Defensive midfielder Albert Nadj is struggling with a thigh injury, but is expected to pass a late fitness test, while Vladimir Ivic is still recovering from a pre-season fracture of a bone in his foot.
Marseille: 1-Vedran Runje; 19-Rudolf Skacel, 4-Daniel van Buyten, 12-Abdoullaye Meite, 8-Sebastien Perez; 18-Camel Meriem, 15-Pascal Johansen, 29-Fabio Celstini; 9-Mido, 20-Steve Marlet, 11-Didier Drogba.
Partizan: 1-Radovan Radakovic; 2-Milivoje Cirkovic, 15-Nikola Malbasa, 16-Taribo West, 24-Branko Savic; 4-Igor Duljaj, 28-Albert Nadj, 14-Nenad Djordjevic, 22-Sasa Ilic; 9-Andrija Delibasic, 17-Ivica Ilie.
Referee: Domenico Messina (Italy)
LAZIO v SPARTA PRAGUE
Dutch defender Jaap Stam returns to steady Lazio's defence after they shipped two goals in four minutes to draw 2-2 with Serie A minnows Empoli last weekend.
In midfield, pacy Brazilian winger Cesar is still recovering from a foot injury and his place on the left should be taken by Sergio Conceicao.
Sparta Prague will welcome playmaker Lukas Zelenka back into their European campaign after he missed more than a month with a broken collarbone. Zelenka was inspirational in last weekend's 4-0 demolition of bottom club Chmel Blsany, the Czech champions' first away win this season.
However, Slovak wingback Martin Petras is out for at least one month after breaking a bone in his foot during their 1-0 home defeat by Chelsea. Jan Flachbart is set to replace him.
In-form striker Marek Kincl is expected to get the nod ahead of Serbia and Montenegro's Igor Gluscevic.
Lazio: 1-Angelo Peruzzi; 22-Massimo Oddo, 31-Jaap Stam, 11-Sinisa Mihajlovic, 19-Giuseppe Favalli; 14-Stefano Fiore, 4-Demetrio Albertini, 10-Dejan Stankovic, 53-Sergio Conceicao; 9-Bernardo Corradi, 7-Claudio Lopez.
Sparta: 29-Jaromir Blazek; 5-Jan Flachbart, 8-Tomas Huebschman, 17-Petr Johana, 3-Vladimir Labant; 8-Karel Poborsky, 15-Radoslav Kovac, 20-Jiri Nemec, 7-Lukas Zelenka; 9-Marek Kincl, 14-Libor Sionko
Referee: Claude Colombo (France)
CHELSEA v BESIKTAS
England full back John Terry has shrugged off a calf injury sustained during training. French international duo William Gallas, the unlikely scorer in Prague a fortnight ago, and Marcel Desailly are likely to hold the fort at the back as they did against Aston Villa last Saturday. French midfielder Emmanuel Petit is the only doubt after picking up a knock on the knee.
Chelsea, who have won eight of their last nine games and lost only once in their 40 European home games, will be looking for quick movement and goals in their first full home Champions League game for four seasons.
Coach Claudio Ranieri has a wealth of players with European experience to choose from and, though he has said he wants to rotate players to keep them fresh, could yet include Dutch striker Jimmy Floyd Hasselbaink, their top scorer this season and the matchwinner in the 1-0 victory over Villa.
Besiktas playmaker Sergen Yalcin is not expected to start despite recovering from injury to play in their 5-0 win over Trabzonspor in Istanbul at the weekend.
An injury in Monday training to Sinan Kaloglu may further narrow coach Mircea Lucescu's options in midfield for the Turkish first division leaders. Besiktas have lost all six of their away Champions League games.
Chelsea: 23-Carlo Cudicini; 15-Mario Melchiot, 6-Marcel Desailly, 13-William Gallas, 18-Wayne Bridge; 20-Juan Sebastian Veron; 4-Claude Makelele; 8-Frank Lampard; 11-Damien Duff; 7-Adrian Mutu; 21-Hernan Crespo.
Besiktas: 1-Oscar Cordoba; 30-Zago, 5-Ronaldo Guiaro, 4-Ahmet Yildirim, 3-Tayfur Havutcu; 20-Federico Giunti, 17-Kaan Dobra, 19-Ibrahim Uzulmez, 9-Daniel Pancu; 26-Ilhan Mansiz, 67-Metin Tumer
Referee: Lucilio Cardoso Cortez Batista (Portugal)
CELTA VIGO v AC MILAN
Celta recorded their first league win of the season when they came from two goals behind to claim a 3-2 victory at home to Valladolid in the Primera Liga on Saturday, but coach Miguel Angel Lotina faces some serious selection problems.
Central midfield pairing Jose Ignacio and Peter Luccin are both suspended and are likely to be replaced by an experimental formation of Brazilian duo Vagner and Everton Giovanella.
Former Arsenal defender Silvinho is doubtful because of an ankle injury, but midfielder Jesuli should be available despite suffering from a back problem.
Striker Savo Milosevic, who scored twice on Saturday, is suffering from pain in his heel but is still likely to play.
Milan striker Filippo Inzaghi looks set to start after making a rapid recovery from a neck injury.
Inzaghi, who has been in devastating form for club and country, was expected to miss the match following a collision with Perugia goalkeeper Zeljko Kalac nine days ago.
Gritty midfielder Gennaro Gattuso starts a two-match ban after being red-carded in their 1-0 win over Ajax and should be replaced by Massimo Ambrosini.
Celta Vigo: 1-Pablo Cavallero; 2-Juan Velasco, 4-Fernando Caceres, 23-Sergio, 14-Juanfran; 7-Vagner, 5-Everton Giovanella, 20-Jesuli, 10-Alexander Mostovoi, 11-Gustavo Lopez; 9-Savo Milosevic
Milan: 12-Dida; 14-Dario Simic, 13-Alessandro Nesta, 3-Paolo Maldini, 19-Alessandro Costacurta; 23-Massimo Ambrosini, 21-Andrea Pirlo, 22-Kaka; 10-Rui Costa; 7-Andrei Shevchenko, 9-Filippo Inzaghi
Referee: Michael Riley (England)
AJAX AMSTERDAM v CLUB BRUGES
Ajax coach Ronald Koeman is expected to make only one change to the side who thrashed Willem II Tilburg 6-0 on Sunday, with playmaker Rafael van der Vaart coming in for Wesley Sneijder.
Czech defender Zdenek Grygera is still unavailable after injury.
Bruges should start with the defence-minded side who beat Beveren 3-0 at the weekend after two late goals. Forwards Sandy Martens and Andres Mendoza are both suspended after being sent off in the 1-1 draw with Celta Vigo, while midfielder Alin Stoica, who twisted his ankle against the Spaniards, is back in training but unavailable to play.
Belgium right back Olivier De Cock, who is not match-fit after training for only a week following injury, will be replaced by 20-year-old Hans Cornelis. Fellow defender David Rozenhal, who has an eye socket problem, has been training with a protective mask and is doubtful.
Ajax: 1-Bogdan Lobont; 2-Hatem Trabelsi, 3-Petri Pasanen, 4-Julien Escude, 15-Maxwell; 8-Steven Pienaar, 6-Tomas Galasek, 10-Rafael van der Vaart; 19-Wesley Sonck, 9-Zlatan Ibrahimovic, 7-Tom Soetaers.
Bruges: 13-Tomislav Butina; 25-Hans Cornelis, 26-Birger Maertens, 6-Philippe Clement, 5-Peter Van Der Heyden; 7-Gert Verheyen, 3-Timmy Simons, 8-Gaetan Englebert, 16-Serhiy Serebrennikov, 17-Ivan Gvozdenovic; 9-Bengt Saeternes.
Referee: Graham Barber (England) (Yahoo)